产物分类
Product Category相关文章
Related Articles驴抗兔IgG H&L抗血清注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
信号转导蛋白亚基6抗体注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity. Stabilizes RFWD2/COP1 through reducing RFWD2 auto-ubiquitination and decelerating RFWD2 turnover rate, hence regulates the ubiquitination of RFWD2 targets.
驴抗豚鼠IgG H&L抗血清免疫原:Native Guinea pig IgG
羊抗鸡IgG H&L抗血清注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
电话
微信扫一扫